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Systemic Lupus Erythematosus (SLE)

Overview

Systemic lupus erythematosus (SLE), commonly known as lupus, is a chronic autoimmune disease in which the immune system
attacks healthy tissues, causing inflammation and damage in multiple organs.

Symptoms of Lupus (SLE)

  • Fatigue and weakness
  • Joint pain and swelling
  • Skin rashes, especially a butterfly-shaped rash on the face
  • Sensitivity to sunlight (photosensitivity)
  • Fever
  • Hair loss
  • Kidney, heart, or lung involvement in severe cases

Causes & Risk Factors

The exact cause of lupus is unknown, but several factors may increase risk:

  • Autoimmune dysfunction
  • Genetic predisposition
  • Hormonal influences (more common in women)
  • Environmental triggers such as sun exposure or infections

How to Diagnose Lupus

Lupus can be challenging to diagnose and typically involves multiple evaluations:

  • Clinical evaluation and symptom review
  • Blood tests (ANA, anti-dsDNA, anti-Smith antibodies)
  • Urine tests for kidney involvement
  • Imaging and other organ-specific tests

Treatment Options

While there is no cure, lupus can be managed effectively with treatment and lifestyle changes.

  • Anti-inflammatory medications
  • Immunosuppressive drugs
  • Corticosteroids
  • Lifestyle modifications (sun protection, stress management)

When to Seek Medical Advice

Consult a healthcare provider if you experience persistent fatigue, joint pain, unexplained rashes, or multi-system symptoms.